Denigma Buck Institute Health Extension
Polymorphism: 11 SNPs, not specified





Location: 7p13-p12

Factor:
- Symbol: IGFBP1
- Name: insulin-like growth factor binding protein 1
- Entrez ID: 3484
- Ensembl ID: ENSG00000146678

Factors:
  • IGFBP1 insulin-like growth factor binding protein 1 ( 3484 / ENSG00000146678 )

    • Ethnicity: Caucasian
    Age of cases: 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 132

    Statistics
    - Number of cases/controls: 317 vs 603;279 vs 797;383 vs 363 (initial)
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: In 1st and 2nd Cohort, Two methods: template directed primer extension with fluorescence polarization detection (FP- TDI, AcycloPrime II detection kit, Perkin Elmer, Boston, MA, USA) (Hsu & Kwok, 2003) and SNPstream 48plex (Beckman Coulter, Fullerton

    Reference:
    19489743: Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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