Polymorphism: rs2802292
rs2802292
(
SNPedia |
23andMe
)
Location: 6q21
Factor:
- Symbol: FOXO3
- Name: forkhead box O3
- Entrez ID: 2309
- Ensembl ID: ENSG00000118689
Factors:
FOXO3
forkhead box O3
(
2309
/
ENSG00000118689
)
Description:
Higher GT & GG genotype in cases_x000D_. OR - homozygous minor vs. homozygous major alleles = 2.75 (p=0.0007)x000D. OR - heterozygous vs. homozygous major alleles = 1.91 (p=0.0003)
Ethnicity:
Japanese
Age of cases: minimum 95; mean 97.9
Shorter lived allele: T
Statistics
- Number of cases/controls: 213 vs 402 (initial)
- p-value:
0.0001
[<.0001]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: ABI Prism 7000 Sequence Detection System
Reference:
18765803: FOXO3A genotype is strongly associated with human longevity.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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