Polymorphism: APOE4
Location: 19q13.31
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Factors:
APOE
apolipoprotein E
(
348
/
ENSG00000130203
)
Description:
Aim: connection of effectiveness of beta-carotene treatment of Alzheimer disease with the presence or absence of APOE4 allele and some other factors of life.
Note: longer-lived allele
Ethnicity:
American
Age of cases: 70-79 (duration of study - 7 years)
Shorter lived allele: e4
Statistics
- Number of cases/controls: 106 vs 349 (initial)
- p-value:
0.71
- Significant: No
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
16799145: Association between serum beta-carotene levels and decline of cognitive function in high-functioning older persons with or without apolipoprotein E 4 alleles: MacArthur studies of successful aging.
Choice: Discard
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
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