Denigma Buck Institute Health Extension
Polymorphism: rs28359172
rs28359172 ( SNPedia | 23andMe )

Variant Type: SNP

Factor:
- Symbol: MT-ND5
- Entrez ID: 4540

Factors:
  • MT-ND5 ( 4540 / )

    • Ethnicity: Chinese
    Age of cases: 90–100
    Shorter lived allele: G
    Finding: Positive

    Statistics
    - Number of cases/controls: 98 vs 117 (initial)
    - Odds ratio: 0.296
    - p-value: 0.003 [0.003]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: DYEnamic ET Terminator Cycle Sequencing Premix Kit (Amersham Pharmacia Biotech, Piscataway, NJ, USA) on an ABI Prism 3730xl Genetic Analyser (Applied Biosystems, Foster City, CA, USA)

    Reference:
    18759861: Mitochondrial DNA haplogroups in a Chinese Uygur population and their potential association with longevity.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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