Denigma Buck Institute Health Extension
Polymorphism: rs1801274
rs1801274 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 1q23

Factor:
- Symbol: FCGR2A
- Name: Fc fragment of IgG, low affinity IIa, receptor (CD32)
- Entrez ID: 2212
- Ensembl ID: ENSG00000143226

Factors:
  • FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) ( 2212 / ENSG00000143226 )


    • Description:

    Three age groups (adult, elderly and centenarian)

    Ethnicity: German
    Age of cases: 100–110/ mean101.3
    Shorter lived allele: (SNP is His/Arg)
    Finding: Negative

    Statistics
    - Number of cases/controls: 408 vs 446 vs 454 (initial)
    - p-value: 0.05 [> 0.05]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene

    Reference:
    16893392: The FCGR2A--Arg131 variant is no major mortality factor in the elderly--evidence from a German centenarian study.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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