Polymorphism: rs2542052
rs2542052 ( SNPedia | 23andMe )

Location: 11q23.3

Factor:
- Symbol: APOC3
- Name: apolipoprotein C-III
- Entrez ID: 345
- Ensembl ID: ENSG00000110245

Factors:
  • APOC3 apolipoprotein C-III ( 345 / ENSG00000110245 )

  • Ethnicity: Ashkenazi Jewish
    Age of cases: mean age 98.2
    Shorter lived allele: A

    Statistics
    - Number of cases/controls: Centenarians (n = 213) their offspring (n = 216) vs 258 (initial)
    - p-value: 0.0001 [<0.0001]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: A multilocus PCR

    Reference:
    16602826: Lipoprotein genotype and conserved pathway for exceptional longevity in humans.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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