Polymorphism: HLA-DRB1*1101


Location: 6p21.3

Factor:
- Symbol: HLA-DRB1
- Name: major histocompatibility complex, class II, DR beta 1
- Entrez ID: 3123
- Ensembl ID: ENSG00000196126

Factors:
  • HLA-DRB1 major histocompatibility complex, class II, DR beta 1 ( 3123 / ENSG00000196126 )


  • Description:

    Decreased frequency of HLA-DRB11101 allele in elderly females when compared to the other HLA-DRB111 alleles from young women. Not Signif.

    Ethnicity: Mexican
    Age of cases: 86.2

    Statistics
    - Number of cases/controls: 71 vs 99 (initial)
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: Polymerase chain reaction sequence specific oligonucleotide (PCR-SSO) reverse dot blot using the Dynal RELI SSO system (Hoffman-La Roche Ltd. and Roche Molecular Systems, Inc., Alameda, CA)

    Reference:
    16269080: Human leukocyte antigen class I, class II, and tumor necrosis factor-alpha polymorphisms in a healthy elder Mexican Mestizo population.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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