Denigma Buck Institute Health Extension
Polymorphism: 1/s


Location: 17q11.2

Factor:
- Symbol: 5HTT
- Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Entrez ID: 6532
- Ensembl ID: ENSG00000108576

Factors:
  • 5HTT solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 ( 6532 / ENSG00000108576 )


    • Description:

    The effect was observed only for women

    Ethnicity: Japanese
    Age of cases: 101.2
    Shorter lived allele: S

    Statistics
    - Number of cases/controls: 265 vs 225 (initial)
    - p-value: 0.05 [<0.05]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR-RFLP

    Reference:
    16095668: Contribution of an affect-associated gene to human longevity: prevalence of the long-allele genotype of the serotonin transporter-linked gene in Japanese centenarians.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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