Polymorphism: rs1801282
rs1801282
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 3p25
Factor:
- Symbol: PPARG
- Name: peroxisome proliferator-activated receptor gamma
- Entrez ID: 5468
- Ensembl ID: ENSG00000132170
Factors:
PPARG
peroxisome proliferator-activated receptor gamma
(
5468
/
ENSG00000132170
)
Description:
Significance in males only. Heterozygotes for SNP had increased presence in long-lived sample.
Ensembel notes rs1805192 as well in this location.
Ethnicity:
Caucasian
Age of cases: 86 to 109; median age 99
Shorter lived allele: G
Finding: Positive
Statistics
- Number of cases/controls: 222 vs 250 (initial)
- p-value:
0.035
[0.035]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR restriction fragment length polymorphism. The fragments were separated on agarose gel.
Reference:
15236769: Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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