Polymorphism: rs1799752
rs1799752 ( SNPedia | 23andMe )

Location: 17q23.3

Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640

Factors:
  • ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ( 1636 / ENSG00000159640 )

  • Ethnicity: French
    Age of cases: 100.6 years
    Shorter lived allele: Insertion

    Statistics
    - Number of cases/controls: 394 vs 238 (initial)
    - p-value: 0.025 [0.025]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR for segment, located in a repetitive Alu sequence in intron 16

    Reference:
    9761238: Plasma concentration, kinetic constants, and gene polymorphism of angiotensin I-converting enzyme in centenarians.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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