Polymorphism: rs3892097, rs35742686, rs1135824, rs35742686
rs3892097, ( SNPedia | 23andMe )
rs35742686, ( SNPedia | 23andMe )
rs1135824, ( SNPedia | 23andMe )
rs35742686 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 22q13.1

Factor:
- Symbol: CYP2D6
- Name: cytochrome P450, family 2, subfamily D, polypeptide 6
- Entrez ID: 1565
- Ensembl ID: ENSG00000100197

Factors:
  • CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 ( 1565 / ENSG00000100197 )


  • Description:

    The odds ratio is given to poor metabolism

    pvalue = 0.02<p<0.05 (invalid literal for float(): 0.020.05)

    Ethnicity: Danish
    Age of cases: 95 and over
    Shorter lived allele: CYP2D6*1

    Statistics
    - Number of cases/controls: 240 vs 325 (initial)
    - Odds ratio: 1.36
    - p-value: 0.05 [0.02<p<0.05]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: allele-specific PCR, long PCR

    Reference:
    9754988: Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevitY. Role of CYP2D6 and CYP2C19 in longevity.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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