Polymorphism: rs3892097, rs35742686, rs1135824, rs35742686
rs3892097,
(
SNPedia |
23andMe
)
rs35742686,
(
SNPedia |
23andMe
)
rs1135824,
(
SNPedia |
23andMe
)
rs35742686
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 22q13.1
Factor:
- Symbol: CYP2D6
- Name: cytochrome P450, family 2, subfamily D, polypeptide 6
- Entrez ID: 1565
- Ensembl ID: ENSG00000100197
Factors:
CYP2D6
cytochrome P450, family 2, subfamily D, polypeptide 6
(
1565
/
ENSG00000100197
)
Description:
The odds ratio is given to poor metabolism
pvalue = 0.02<p<0.05 (invalid literal for float(): 0.020.05)
Ethnicity:
Danish
Age of cases: 95 and over
Shorter lived allele: CYP2D6*1
Statistics
- Number of cases/controls: 240 vs 325 (initial)
- Odds ratio: 1.36
- p-value:
0.05
[0.02<p<0.05]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: allele-specific PCR, long PCR
Reference:
9754988: Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevitY. Role of CYP2D6 and CYP2C19 in longevity.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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