Polymorphism: VNTR (Variable Number of Tandem Repeats)
Location: 2p24-p23
Factor:
- Symbol: APOB
- Name: apolipoprotein B (including Ag(x) antigen)
- Entrez ID: 338
- Ensembl ID: ENSG00000084674
Factors:
APOB
apolipoprotein B (including Ag(x) antigen)
(
338
/
ENSG00000084674
)
Description:
Significant in females only. For females: P=0.003 vs. whole population; P=0.06 vs all controls; P=0.001 vs. male controls.
Ethnicity:
Italian
Age of cases: mean age is 102 years
Shorter lived allele: 35 or more tandem repeats
Statistics
- Number of cases/controls: 143 vs 158 (initial)
- p-value:
0.003
[P = 0.003]
- Significant: yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR-VNTR (variable number of tandem repeats)
Reference:
9050915: DNA multiallelic systems reveal gene/longevity associations not detected by diallelic systems. The APOB locus.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
Edit
(
Admin) |
Delete