Polymorphism: rs1061581 - rs1008438 - rs2227956
rs1061581
(
SNPedia |
23andMe
)
rs1008438
(
SNPedia |
23andMe
)
rs2227956
(
SNPedia |
23andMe
)
Variant Type: Haplotype
Location: 5q31.1
Factor:
- Symbol: Hsp70Ba
- Name: Heat-shock-protein-70Ba
- Entrez ID: 44921
- Ensembl ID: FBgn0013277
Factors:
HSPA1A
heat shock 70kDa protein 4
(
3308
/
ENSG00000170606
)
Ethnicity:
Danish
Age of cases: Mean age 92.8 +/- 0.4
Longer lived allele: G-C-T (haplotype)
Finding: Positive
Statistics
- Number of cases/controls: 168 cases (initial)
- Odds ratio: 0.55
- Odds ratio type: Shorter
- p-value:
0.015
[0.015 (females)]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: LightCycler system (Roche Applied Sciences), GAUSS programming package
Reference:
20388090: Anti-inflammatory heat shock protein 70 genes are positively associated with human survival.
Choice: Clean
Created: July 2, 2013, 2:33 a.m.
Updated: Aug. 26, 2013, 1:44 p.m.
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