Polymorphism: rs1061581 - rs1008438 - rs2227956
rs1061581 ( SNPedia | 23andMe )

rs1008438 ( SNPedia | 23andMe )

rs2227956 ( SNPedia | 23andMe )

Variant Type: Haplotype
Location: 5q31.1

Factor:
- Symbol: Hsp70Ba
- Name: Heat-shock-protein-70Ba
- Entrez ID: 44921
- Ensembl ID: FBgn0013277

Factors:
  • HSPA1A heat shock 70kDa protein 4 ( 3308 / ENSG00000170606 )

  • Ethnicity: Danish
    Age of cases: Mean age 92.8 +/- 0.4
    Longer lived allele: G-C-T (haplotype)
    Finding: Positive

    Statistics
    - Number of cases/controls: 168 cases (initial)
    - Odds ratio: 0.55
    - Odds ratio type: Shorter
    - p-value: 0.015 [0.015 (females)]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: LightCycler system (Roche Applied Sciences), GAUSS programming package

    Reference:
    20388090: Anti-inflammatory heat shock protein 70 genes are positively associated with human survival.

    Choice: Clean
    Created: July 2, 2013, 2:33 a.m.
    Updated: Aug. 26, 2013, 1:44 p.m.

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