Polymorphism: VNTR polymorphism



Location: 7p21

Factor:
- Symbol: IL6
- Name: interleukin 6 (interferon, beta 2)
- Entrez ID: 3569
- Ensembl ID: ENSG000001

Factors:
  • IL6 interleukin 6 (interferon, beta 2) ( 3569 / ENSG000001 )


  • Description:

    Our findings suggested that the presence of the IL6 VNTR allele B could be detrimental for reaching extreme longevity.

    Ethnicity: Italian
    Age of cases: 100 years vs. 52 years

    Statistics
    - Number of cases/controls: 61 centenarians and 94 middle-aged subjects (initial)
    - Odds ratio: 0.56
    - p-value: 0.07 [0.07]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology:

    Reference:
    17506774: Interleukin 6 variable number of tandem repeats (VNTR) gene polymorphism in centenarians.

    Choice: Curate
    Created: July 2, 2013, 2:33 a.m.
    Updated: Aug. 26, 2013, 1:44 p.m.

    Edit (Admin) | Delete