Polymorphism: VNTR polymorphism
Location: 7p21
Factor:
- Symbol: IL6
- Name: interleukin 6 (interferon, beta 2)
- Entrez ID: 3569
- Ensembl ID: ENSG000001
Factors:
IL6
interleukin 6 (interferon, beta 2)
(
3569
/
ENSG000001
)
Description:
Our findings suggested that the presence of the IL6 VNTR allele B could be detrimental for reaching extreme longevity.
Ethnicity:
Italian
Age of cases: 100 years vs. 52 years
Statistics
- Number of cases/controls: 61 centenarians and 94 middle-aged subjects (initial)
- Odds ratio: 0.56
- p-value:
0.07
[0.07]
- Significant: yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology:
Reference:
17506774: Interleukin 6 variable number of tandem repeats (VNTR) gene polymorphism in centenarians.
Choice: Curate
Created: July 2, 2013, 2:33 a.m.
Updated: Aug. 26, 2013, 1:44 p.m.
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