Denigma Buck Institute Health Extension
Polymorphism: rs3220637
rs3220637 ( SNPedia | 23andMe )

Variant Type: STR
Location: 19q13.2

Factor:
- Symbol: XRCC1
- Name: X-ray repair complementing defective repair in Chinese hamster cells 1
- Entrez ID: 7515
- Ensembl ID: ENSG00000073050

Factors:
  • XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 ( 7515 / ENSG00000073050 )


    • Description:

    In article rsid is not mentioned, but I think that XRCC1 3`-UTR (AC)n microsatellite should be rs3220637.

    Ethnicity: British
    Age of cases: Mean age 70
    Shorter lived allele: 16
    Finding: Positive

    Statistics
    - Number of cases/controls: 430 (case) vs 290 (initial)
    - Odds ratio type: Shorter
    - p-value: 0.0005 [0.855]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: ABI Prism 310 Genetic Analyser

    Reference:
    16518718: Genotype profiles of loci encoding DNA repair enzymes in newborn and elderly populations: no evidence of association with longevity.

    Choice: Clean
    Created: July 2, 2013, 2:33 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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