Polymorphism: F5 G1691A
Location: 1q23
Factor:
- Symbol: F5
- Name: coagulation factor V (proaccelerin, labile factor)
- Entrez ID: 2153
- Ensembl ID: ENSG00000198734
Factors:
F5
coagulation factor V (proaccelerin, labile factor)
(
2153
/
ENSG00000198734
)
Description:
The frequency of the G1691A factor V Leiden mutation decreased with age, which indicates a shorter survival time among A1691 allele carriers in the Polish population.
Ethnicity:
Polish
Age of cases: >95 years versus 44 years
Statistics
- Number of cases/controls: 400 neonates (187 female and 312 male), 184 healthy adults (129 female and 55 male), and 432 long-lived individuals (343 women and 89 men). (initial)
- p-value:
0.002
[< 0.002]
- Significant: yes
Study Design
- Classifications:
Longevity-Associated
- Study type: -
- Technology: PCR-RFLP
Reference:
20720309: An age-related decrease in factor V Leiden frequency among Polish subjects.
Choice: Curate
Created: July 2, 2013, 2:33 a.m.
Updated: Aug. 26, 2013, 1:41 p.m.
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