Polymorphism: rs12050077
rs12050077 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 14q31

Factor:
- Symbol: TSHR
- Name: thyroid stimulating hormone receptor
- Entrez ID: 7253
- Ensembl ID: ENSG00000165409

Factors:
  • TSHR thyroid stimulating hormone receptor ( 7253 / ENSG00000165409 )

  • Ethnicity: Ashkenazi Jewish
    Age of cases: Median age 69
    Shorter lived allele: A
    Longer lived allele: G
    Finding: Positive

    Statistics
    - Number of cases/controls: 366 vs 163 (initial)
    - Odds ratio: 1.32
    - p-value: 0.01 [0.01]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR & sequencing

    Reference:
    19837933: Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity.

    Choice: Curate
    Created: July 2, 2013, 2:33 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

    Edit (Admin) | Delete