Polymorphism: -
Location: 11p15.5
Factor:
- Symbol: TH
- Name: tyrosine hydroxylase
- Entrez ID: 7054
- Ensembl ID: ENSG00000180176
Factors:
TH
tyrosine hydroxylase
(
7054
/
ENSG00000180176
)
Description:
southern Italy (n=92 centenarians, age range 100–108 years old, mean 101.9; and n=97 controls aged 20–60 years old, mean 41.44), northern-central Italy (n=307 centenarians, age range 99–109 years old, mean 101.0; and n=352 controls aged 17–60 years old, mean 41.2), Germany (n=376 centenarians, age range 100–110 years old, mean 104.41; and 376 controls aged 60–75 years old, mean 67.52) and France (n=546 centenarians, age range 99–106 years old, mean 103.1; and 315 controls aged 18–70 years old, mean 51.2).
Ethnicity:
French,
German,
Italian
Age of cases: centenarians; see notes
Statistics
- Number of cases/controls: see notes; stratified by population; total = 1321 cases versus 1140 controls (initial)
- p-value:
0.05
[>0.05]
- Significant: no
Study Design
- Classifications:
No Age Effect
- Study type: -
- Technology: SNPlex technology
Reference:
19367319: Human longevity and 11p15.5: a study in 1321 centenarians.
Choice: Curate
Created: July 2, 2013, 2:33 a.m.
Updated: Aug. 26, 2013, 1:37 p.m.
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