Denigma Buck Institute Health Extension
Polymorphism: rs1061581
rs1061581 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 6p21.3

Factor:
- Symbol: HSPA1B
- Name: heat shock 70kDa protein 1A
- Entrez ID: 3303
- Ensembl ID: ENSG00000204389

Factors:
  • HSPA1A heat shock 70kDa protein 1A ( 3303 / ENSG00000204389 )


    • Description:

    Applies to females only. Detailed P-value data: For genotype HSPA1B-AA: 0.039 Relative risk is 2.764.

    Trivial name is 1267A>G.

    Ethnicity: Danish
    Age of cases: Mean age 92.8 +/- 0.4
    Shorter lived allele: А
    Finding: Positive

    Statistics
    - Number of cases/controls: 168 cases (initial)
    - Odds ratio: 2.764
    - Odds ratio type: Shorter
    - p-value: 0.039 [0.039 (females)]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: LightCycler system (Roche Applied Sciences), GAUSS programming package

    Reference:
    20388090: Anti-inflammatory heat shock protein 70 genes are positively associated with human survival.

    Choice: Clean
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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