Polymorphism: rs1008438
rs1008438
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 6p21.3
Factor:
- Symbol: HSPA1A
- Name: heat shock 70kDa protein 1A
- Entrez ID: 3303
- Ensembl ID: ENSG00000204389
Factors:
HSPA1A
heat shock 70kDa protein 1A
(
3303
/
ENSG00000204389
)
Description:
Applies to females only.
Detailed P-value data: For genotype HSPA1A-AA: 0.016; HSPA1A-AC: 0.056
Relative risk for living longer for AA genotype is 3,864.
Trivial name is -100 A/C.
Ethnicity:
Danish
Age of cases: Mean age 92.8 +/- 0.4
Shorter lived allele: А
Finding: Positive
Statistics
- Number of cases/controls: 168 cases (initial)
- Odds ratio: 3.864
- Odds ratio type: Shorter
- p-value:
0.016
[0.016 (females)]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: LightCycler system (Roche Applied Sciences), GAUSS programming package
Reference:
20388090: Anti-inflammatory heat shock protein 70 genes are positively associated with human survival.
Choice: Clean
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.
Edit
(
Admin) |
Delete