Denigma Buck Institute Health Extension
Polymorphism: APOE polymorphism



Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )

    • Ethnicity: Greek
    Age of cases: >80
    Shorter lived allele: epsilon4

    Statistics
    - Number of cases/controls: 80 vs 391 (initial)
    - p-value: 0.02 [0.02]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Taq polymerase (Gibco)

    Reference:
    17234815: Lower prevalence of epsilon 4 allele of apolipoprotein E gene in healthy, longer-lived individuals of Hellenic origin.

    Choice: Curate
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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