Polymorphism: rs1346044
rs1346044
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 8p12
Factor:
- Symbol: WRN
- Name: Werner syndrome, RecQ helicase-like
- Entrez ID: 7486
- Ensembl ID: ENSG00000165392
Factors:
WRN
Werner syndrome, RecQ helicase-like
(
7486
/
ENSG00000165392
)
Description:
Leiden 85-plus Study. "In conclusion, the present study shows that the i1-C/T, L1074F [rs2725362] and C1367R variations in the WRN gene do not influence the sensitivity or resistance to... the course of aging."
Trivial name is C1367R
Ethnicity:
Dutch
Age of cases: >/= 85
Finding: Negative
Statistics
- Number of cases/controls: cases: 1245 (Cohort '87: 682; Cohort '97: 563); vs controls: 247 (initial)
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: Assay-by-Design, qPCR core kit, Sequenom MassARRAYtm
Reference:
16405962: Impact of genetic variations in the WRN gene on age related pathologies and mortality.
Choice: Clean
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 9, 2014, 11:32 p.m.
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