Polymorphism: rs11585393
rs11585393 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 1p34.2

Factor:
- Symbol: FOXO6
- Name: forkhead box O6
- Entrez ID: 100132074

Factors:
  • FOXO6 forkhead box O6 ( 100132074 / )


  • Description:

    Our results suggest that in Germans [nor Italians], none of the three genes plays a significant role in the ability to reach old age.

    Ethnicity: German
    Age of cases: Mean age 98.8
    Finding: Negative

    Statistics
    - Number of cases/controls: 1447 vs 1029 (initial) | 166 vs 216 (Italian) (replication)
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: SNPIex Genotyping System, TaqMan SNP Genotyping Assays, Infinium II Assay-HumanHap 317K duo BeadChip system

    Reference:
    21388494: Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans.

    Choice: Clean
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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