Denigma Buck Institute Health Extension
Polymorphism: rs5981072
rs5981072 ( SNPedia | 23andMe )

Variant Type: SNP
Location: Xq13.1

Factor:
- Symbol: FOXO4
- Name: forkhead box O4
- Entrez ID: 4303
- Ensembl ID: ENSG00000184481

Factors:
  • FOXO4 forkhead box O4 ( 4303 / ENSG00000184481 )


    • Description:

    Our results suggest that in Germans [nor Italians], none of the three genes plays a significant role in the ability to reach old age.

    Ethnicity: German
    Age of cases: Mean age 98.8
    Finding: Negative

    Statistics
    - Number of cases/controls: 1447 vs 1029 (initial) | 166 vs 216 (Italian) (replication)
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: SNPIex Genotyping System, TaqMan SNP Genotyping Assays, Infinium II Assay-HumanHap 317K duo BeadChip system

    Reference:
    21388494: Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans.

    Choice: Clean
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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