Polymorphism: V465A
Location: 3q11.2
Factor:
- Symbol: GABRR3
- Name: gamma-aminobutyric acid (GABA) receptor, rho 3
- Entrez ID: 200959
- Ensembl ID: ENSG00000183185
Factors:
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
(
200959
/
ENSG00000183185
)
Description:
...a novel nsSNP in GABRR3 (p.V465A) was significantly depleted in centenarians... as compared to controls…
Ethnicity:
Ashkenazi Jewish
Age of cases: Centenarians
Statistics
- Number of cases/controls: 390 vs 410 (initial)
- p-value:
0.04
[0.04]
- Significant: Nominally
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: Agilent SureSelect in-solution target capture, Agilent eArray, BWA version 0.5.9, Picard, Genome Analysis Toolkit (GATK), iPLEX MassArray assays, MassARRAY Typer, SNP & Variation suite version 7.6.11
Reference:
23376243: Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing.
Choice: Curate
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:33 p.m.
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