Denigma Buck Institute Health Extension
Polymorphism: rs1061581
rs1061581 ( SNPedia | 23andMe )

Location: 6p21.3

Factor:
- Symbol: HSPA1L
- Name: heat shock 70kDa protein 1-like
- Entrez ID: 3305
- Ensembl ID: ENSG00000204390

Factors:
  • HSPA1L heat shock 70kDa protein 1-like ( 3305 / ENSG00000204390 )


    • Description:

    Applies only to females. High LD among rs1008438, rs1061581, and rs2227956. "Pair-wise LD calculated among the three markers also showed a high LD (D'=1) between the SNP at HSPA1A [rs1008438] with the other two SNPs..."

    Ethnicity: Danish
    Age of cases: 92.8
    Shorter lived allele: A

    Statistics
    - Number of cases/controls: 157 vs 62 (initial)
    - p-value: 0.04 [0.04]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR based probes

    Reference:
    16804002: Heat-shock protein 70 genes and human longevity: a view from Denmark.

    Choice: Curate
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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