Denigma Buck Institute Health Extension
Polymorphism: TNF haplotypes



Location: 6p21.3

Factor:
- Symbol: TNF
- Name: tumor necrosis factor
- Entrez ID: 7124
- Ensembl ID: ENSG00000232810

Factors:
  • TNF tumor necrosis factor ( 7124 / ENSG00000232810 )

    • Ethnicity: Bulgarian
    Age of cases: Age range: 65-99
    Longer lived allele: −1031 C/C, −863 C/A, −857 C/C, −308 G/G, +489 G/G

    Statistics
    - Number of cases/controls: 60 vs 50 (initial)
    - p-value: 0.01 [0.01]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR-based sequencing

    Reference:
    21299522: 'Immunogenetics of Aging': report on the activities of the 15th International HLA and Immunogenetics Working Group and 15th International HLA and Immunogenetics Workshop.

    Choice: Curate
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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