Denigma Buck Institute Health Extension
Polymorphism: rs189037
rs189037 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 11q22-q23

Factor:
- Symbol: ATM
- Name: ataxia telangiectasia mutated
- Entrez ID: 472
- Ensembl ID: ENSG00000149311

Factors:
  • ATM ataxia telangiectasia mutated ( 472 / ENSG00000149311 )


    • Description:

    Centenarian group referred to as LLI (Long-lived individuals) group. "We did not find any significant difference in the distribution of C/T genotypes in the LLI group compared to the controls"

    Ethnicity: Italian
    Age of cases: Mean age 98.7 +/- 5.1
    Finding: Negative

    Statistics
    - Number of cases/controls: 128 vs 150 (initial)
    - Odds ratio: 1.45
    - p-value: 0.12 [0.12]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: KASPar (fluorescence-based competitive allele-specific PCR system assay), COMPARE2 software

    Reference:
    22960875: Ataxia-telangiectasia mutated (ATM) genetic variant in Italian centenarians.

    Choice: Curate
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

    Edit (Admin) | Delete