Denigma Buck Institute Health Extension
Polymorphism: intron 2 VNTR




Variant Type: STR
Location: 2q14.2

Factor:
- Symbol: IL1RN
- Name: interleukin 1 receptor antagonist
- Entrez ID: 3557
- Ensembl ID: ENSG00000136689

Factors:
  • IL1RN interleukin 1 receptor antagonist ( 3557 / ENSG00000136689 )


    • Description:

    The data showed that no statistically significant differences were found between the nonagenarians and controls

    The P value listed is for the allele frequency of A3 found in Table 1

    Ethnicity: Finn
    Age of cases: >90
    Finding: Negative

    Statistics
    - Number of cases/controls: 250 vs 400 (initial)
    - p-value: 0.08 [0.08]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: PCR-RFLP

    Reference:
    11640949: Lack of association between human longevity and polymorphisms of IL-1 cluster, IL-6, IL-10 and TNF-alpha genes in Finnish nonagenarians.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:56 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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