Denigma Buck Institute Health Extension
Polymorphism: HRAS1 3'VNTR



Location: 11p15.5

Factor:
- Symbol: HRAS
- Name: v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- Entrez ID: 3265
- Ensembl ID: ENSG00000174775

Factors:
  • HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog ( 3265 / ENSG00000174775 )

    • Ethnicity: Italian
    Age of cases: Minimum age 100
    Shorter lived allele: a3
    Longer lived allele: non-a3

    Statistics
    - Number of cases/controls: 234 vs 467 (initial)
    - Odds ratio: 1.126
    - p-value: 0.551 [0.551]
    - Significant: no

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR-RFLP

    Reference:
    11943467: An allele of HRAS1 3'variable number of tandem repeats is a frailty allele: implication for an evolutionarily-conserved pathway involved in longevity.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:56 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

    Edit (Admin) | Delete