Denigma Buck Institute Health Extension
Polymorphism: rs1801270
rs1801270 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 6p21.2

Factor:
- Symbol: CDKN1A
- Name: cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- Entrez ID: 1026
- Ensembl ID: ENSG00000124762

Factors:
  • CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) ( 1026 / ENSG00000124762 )

    • Ethnicity: Italian
    Age of cases: 100
    Shorter lived allele: A
    Longer lived allele: C
    Finding: Positive

    Statistics
    - Number of cases/controls: 184 vs 184 (initial)
    - Odds ratio: 0.437
    - p-value: 0.02 [0.02]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Sequenom's chip-based DNA MASSARRAY

    Reference:
    20126416: Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:55 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

    Edit (Admin) | Delete