Denigma Buck Institute Health Extension
Polymorphism: rs4340
rs4340 ( SNPedia | 23andMe )

Location: 17q23.3

Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640

Factors:
  • ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ( 1636 / ENSG00000159640 )

    • Ethnicity: French
    Age of cases: 100+
    Shorter lived allele: I
    Longer lived allele: D

    Statistics
    - Number of cases/controls: 300 vs 160 (initial)
    - Odds ratio: 1.9
    - p-value: 0.001 [0.001]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: unknown (old paper)

    Reference:
    8136829: Genetic associations with human longevity at the APOE and ACE loci.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:45 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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