Polymorphism: APOE4
Location: 19q13.31
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Description:
The E4 frequencies differed significantly across 3 groups (90+ years, 20-35 years, patients with myocardial infarction).
Ethnicity:
Chinese
Age of cases: 90 years or over
Shorter lived allele: High E4 frequency
Finding: Positive
Statistics
- Number of cases/controls: 35 vs 125 (initial)
- p-value:
0.013
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
11780357: Apolipoprotein E gene polymorphism and its association with human longevity in the Uygur nationality in Xinjiang.
Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
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