Polymorphism: APOE e2,e3,e4



Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )

  • Ethnicity: Finn
    Age of cases: Over 100
    Shorter lived allele: E4
    Longer lived allele: e2

    Statistics
    - Number of cases/controls: 185 vs 486 (initial)
    - p-value: 0.05 [0.05]
    - Significant: Borderline

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: plasma electropheresis

    Reference:
    8018664: Aging and genetic variation of plasma apolipoproteins. Relative loss of the apolipoprotein E4 phenotype in centenarians.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:39 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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