Polymorphism: APOE e2,e3,e4



Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )

  • Ethnicity: Ashkenazi Jewish
    Age of cases: 75
    Shorter lived allele: e4
    Longer lived allele: e2
    Finding: Positive

    Statistics
    - Number of cases/controls: 224 vs 441 (initial)
    - Odds ratio: 9.236
    - p-value: 0.01 [0.01]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: ABI SNaPshot kit

    Reference:
    15621215: Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:37 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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