Denigma Buck Institute Health Extension
Polymorphism: rs1801133
rs1801133 ( SNPedia | 23andMe )

Location: 1p36.3

Factor:
- Symbol: MTHFR
- Name: methylenetetrahydrofolate reductase (NAD(P)H)
- Entrez ID: 4524
- Ensembl ID: ENSG00000177000

Factors:
  • MTHFR methylenetetrahydrofolate reductase (NAD(P)H) ( 4524 / ENSG00000177000 )

    • Ethnicity: French
    Age of cases: mean age 100.71
    Shorter lived allele: TT
    Longer lived allele: CT, CC

    Statistics
    - Number of cases/controls: 564 vs. 374 (initial)
    - p-value: 0.06 [0.06]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    9106548: Methylenetetrahydrofolate reductase thermolabile variant and human longevity.

    Choice: Curate_Emily
    Created: July 1, 2013, 10:47 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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