Denigma Buck Institute Health Extension
Polymorphism: rs1800896
rs1800896 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 1q31-q32

Factor:
- Symbol: IL10
- Name: interleukin 10
- Entrez ID: 3586
- Ensembl ID: ENSG00000136634

Factors:
  • IL10 interleukin 10 ( 3586 / ENSG00000136634 )


    • Description:

    Only significant in men Trivial name is -1082G/A

    Ethnicity: Italian
    Age of cases: >100
    Longer lived allele: GG
    Finding: Positive

    Statistics
    - Number of cases/controls: 174 vs 227 (initial)
    - p-value: 0.019 [0.019 (only in males)]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    12676903: Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 -1082 promoter SNP and its interaction with TNF-alpha -308 promoter SNP.

    Choice: Clean
    Created: July 1, 2013, 10:42 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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