Polymorphism: ACE D/I
Location: 17q23.3
Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640
Factors:
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
(
1636
/
ENSG00000159640
)
Description:
689 twins. Participants with the ACE II genotype had marginally poorer survival after follow-up, p<0.02.
Ethnicity:
Danish
Age of cases: Minimum age 73
Shorter lived allele: II
Longer lived allele: DI, DD
Statistics
- Number of cases/controls: 689 (initial)
- p-value:
0.02
[0.02]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Not reported
Reference:
12547486: Angiotensin I-converting enzyme (ACE) gene polymorphism in relation to physical performance, cognition and survival--a follow-up study of elderly Danish twins.
Choice: Curate_Johnny
Created: July 1, 2013, 10:04 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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