Polymorphism: rs3758391
rs3758391
(
SNPedia |
23andMe
)
Location: 10q21.3
Factor:
- Symbol: SIRT1
- Name: sirtuin 1
- Entrez ID: 23411
- Ensembl ID: ENSG00000096717
Factors:
SIRT1
sirtuin 1
(
23411
/
ENSG00000096717
)
Description:
3 groups: centenarians, lon-lived, and controls. "These findings... suggest that there is no noteworthy influence of SIRT1 sequence variation on exceptional human longevity"
Ethnicity:
German
Age of cases: Mean age 101
Statistics
- Number of cases/controls: 386 vs 640 vs 547 (initial)
- p-value:
1.0
[1]
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: Taqman Allelic Discrimination
Reference:
16257164: Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity.
Choice: Curate_Johnny
Created: July 1, 2013, 10:03 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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