Polymorphism: rs1937
rs1937
(
SNPedia |
23andMe
)
Variant Type: SNP
Factor:
- Symbol: TFAM
- Name: transcription factor A, mitochondrial
- Entrez ID: 7019
- Ensembl ID: ENSG00000108064
Description:
Significant difference between groups was observed only with CC genotype, which was present only in centenarian group (with no difference in allele frequencies).
Ethnicity:
Spaniard
Age of cases: 100–111
Shorter lived allele: G
Longer lived allele: CC (genotype)
Finding: Positive
Statistics
- Number of cases/controls: 107 vs 284 (initial)
- p-value:
0.003
- Significant: Yes
Study Design
- Study type: Candidate Region/Gene
- Technology: TaqMan SNP genotyping assay
Reference:
23186209: Mitochondriogenesis genes and extreme longevity.
Choice: Clean
Created: June 30, 2013, 11:53 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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