Polymorphism: rs12778366
rs12778366 ( SNPedia | 23andMe )

Variant Type: SNP

Factor:
- Symbol: SIRT1
- Name: sirtuin 1
- Entrez ID: 23411
- Ensembl ID: ENSG00000096717

Factors:
  • SIRT1 sirtuin 1 ( 23411 / ENSG00000096717 )


  • Description:

    Carriers of minor allele (C) showed redu ed mortality in a healthy population.

    Ethnicity: Dutch
    Age of cases: 36 to 79
    Finding: Positive

    Statistics
    - Number of cases/controls: 1390 (initial)
    - Odds ratio: 0.69
    - Odds ratio type:
    - p-value: 0.025 [0.025]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology:

    Reference:
    23505545: SIRT1 polymorphism, long-term survival and glucose tolerance in the general population.

    Choice: Curate
    Created: Aug. 31, 2014, 9:35 p.m.
    Updated: Aug. 31, 2014, 9:35 p.m.

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