Denigma Buck Institute Health Extension
Polymorphism: rs10491334
rs10491334 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 5q21.3

Factor:
- Symbol: CAMK4
- Name: calcium/calmodulin-dependent protein kinase IV
- Entrez ID: 814
- Ensembl ID: ENSG00000152495

Factors:
  • CAMK4 calcium/calmodulin-dependent protein kinase IV ( 814 / ENSG00000152495 )


    • Description:

    Finding confirmed in replication cohort.

    Ethnicity: Italian
    Age of cases: 90–109
    Finding: Positive

    Statistics
    - Number of cases/controls: 410 vs 553 (initial) | 116 vs 160 (replication)
    - Odds ratio: 0.55
    - Odds ratio type:
    - p-value: 5.29e-05 [0.0000529]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Illumina HumanHap BeadChip 317K duo system

    Reference:
    21612516: Association study on long-living individuals from Southern Italy identifies rs10491334 in the CAMKIV gene that regulates survival proteins.

    Choice: Clean
    Created: Aug. 20, 2013, 9:23 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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