Polymorphism: ?145K


Location: 6p21.3

Factor:
- Symbol: LMP7
- Name: proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
- Entrez ID: 5696
- Ensembl ID: ENSG00000204264

Factors:
  • LMP7 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) ( 5696 / ENSG00000204264 )


  • Description:

    No association with longevity

    odds_ratio = N/A (could not convert string to float: )

    Ethnicity: Italian
    Age of cases: 88+
    Shorter lived allele: K

    Statistics
    - Number of cases/controls: 157 vs 311 (initial)
    - p-value: 0.849
    - Significant: No

    Study Design
    - Study type: Candidate Region/Gene
    - Technology: PCR-RFLP, restriction digest, gel electrophoresis

    Reference:
    11772516: Age dependent impact of LMP polymorphisms on TNFalpha-induced apoptosis in human peripheral blood mononuclear cells.

    Choice: Curate
    Created: June 30, 2013, midnight
    Updated: Aug. 8, 2014, 1:05 p.m.

    Edit (Admin) | Delete