Polymorphism: ?145K
Location: 6p21.3
Factor:
- Symbol: LMP7
- Name: proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
- Entrez ID: 5696
- Ensembl ID: ENSG00000204264
Factors:
LMP7
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
(
5696
/
ENSG00000204264
)
Description:
No association with longevity
odds_ratio = N/A (could not convert string to float: )
Ethnicity:
Italian
Age of cases: 88+
Shorter lived allele: K
Statistics
- Number of cases/controls: 157 vs 311 (initial)
- p-value:
0.849
- Significant: No
Study Design
- Study type: Candidate Region/Gene
- Technology: PCR-RFLP, restriction digest, gel electrophoresis
Reference:
11772516: Age dependent impact of LMP polymorphisms on TNFalpha-induced apoptosis in human peripheral blood mononuclear cells.
Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
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