Polymorphism: rs1800591-rs61733139
rs1800591-rs61733139
(
SNPedia |
23andMe
)
Variant Type: Haplotype
Factor:
- Symbol: MTTP
- Name: microsomal triglyceride transfer protein
- Entrez ID: 4547
- Ensembl ID: ENSG00000138823
Description:
The two MTP polymorphisms are in complete LD. "We found no association of an MTP haplotype with longevity in either of our Leiden studies." Meta-analysis led to same conclusion.
T-Q haplotype was studied. Initial number refers to nonagenarian sib pairs vs partners of the offspring of nonagenarian sib pairs
Ethnicity:
Dutch
Age of cases: Mean age 93.8 ± 3.1
Finding: Negative
Statistics
- Number of cases/controls: 164 vs 261 (initial)
- p-value:
0.93
[0.93]
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: PCR based probes
Reference:
16611701: Chromosome 4q25, microsomal transfer protein gene, and human longevity: novel data and a meta-analysis of association studies.
Choice: Curate
Created: Aug. 11, 2013, 2:09 a.m.
Updated: Aug. 9, 2014, 11:33 p.m.
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