Denigma Buck Institute Health Extension
Polymorphism: rs4646
rs4646 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 15q21.1

Factor:
- Symbol: CYP19
- Name: cytochrome P450, family 19, subfamily A, polypeptide 1
- Entrez ID: 1588
- Ensembl ID: ENSG00000137869

Factors:
  • CYP19 cytochrome P450, family 19, subfamily A, polypeptide 1 ( 1588 / ENSG00000137869 )

    • Ethnicity: Italian
    Age of cases: 90+
    Longer lived allele: T
    Finding: Positive

    Statistics
    - Number of cases/controls: 108 vs 85 (initial)
    - Odds ratio: 1.9
    - Odds ratio type: Longer
    - p-value: 0.04
    - Significant: Yes

    Study Design
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    20819792: Association of CYP19 and ESR1 pleiotropic genes with human longevity.

    Choice: Clean
    Created: June 30, 2013, midnight
    Updated: Aug. 8, 2014, 1:05 p.m.

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