Polymorphism: rs12013673
rs12013673
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: Xq13.1
Factor:
- Symbol: FOXO4
- Name: forkhead box O4
- Entrez ID: 4303
- Ensembl ID: ENSG00000184481
Factors:
FOXO4
forkhead box O4
(
4303
/
ENSG00000184481
)
Description:
Our results suggest that in Germans [nor Italians], none of the three genes plays a significant role in the ability to reach old age.
p-value = 0.696 (allele)
p-value = 0.548 (genotype)
odds ratio = 0.98 (0.86–1.10) (95% C.I.)
Ethnicity:
German
Age of cases: Mean age 98.8
Finding: Negative
Statistics
- Number of cases/controls: 1447 vs 1029 (German) (initial)
| 166 vs 216 (Italian) (replication)
- Odds ratio: 0.98
- p-value:
0.696
[0.548 (genotype)]
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: SNPIex Genotyping System, TaqMan SNP Genotyping Assays, Infinium II Assay-HumanHap 317K duo BeadChip system
Reference:
21388494: Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans.
Choice: Curate
Created: July 29, 2013, 10:16 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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