Denigma Buck Institute Health Extension
Polymorphism: rs10489436
rs10489436 ( SNPedia | 23andMe )

Location: 1p36

Factor:
- Symbol: H6PD
- Name: hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
- Entrez ID: 9563
- Ensembl ID: ENSG00000049239

Factors:
  • H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) ( 9563 / ENSG00000049239 )


    • Description:

    P value reported is min.pval, odds ratio is OR.A.B (from paper)

    Ethnicity: Caucasian
    Age of cases: Median age 104
    Shorter lived allele: A
    Longer lived allele: G

    Statistics
    - Number of cases/controls: 801 vs 914 (initial)
    - Odds ratio: 1.05963369
    - p-value: 0.000883064 [0.000883064]
    - Significant: Nominally yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Illumina: 370 CNV chip v1.0, Human610-Quad v1.0, Human 1 M v1.0

    Reference:
    22279548: Genetic signatures of exceptional longevity in humans.

    Choice: Clean
    Created: July 20, 2013, 10:46 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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