Polymorphism: rs1800896
rs1800896
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 1q32.2
Factor:
- Symbol: IL10
- Name: interleukin 10
- Entrez ID: 3586
- Ensembl ID: ENSG00000136634
Description:
Aim: connection of CVD development with age and IL-10 promotor polymorphism. Several case-control populations in North Italy and Sicily. Several SNPs have been chosen but the most striking data is about mentioned SNP.
Odds ratio = 3.1-3.2
Age of cases: Mean age 67
Shorter lived allele: AA
Longer lived allele: GG
Statistics
- Number of cases/controls: 142 vs 153 (initial)
- Odds ratio: 3.1
- p-value:
0.0003
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
15466015: Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease.
Choice: Dmitrij Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
Edit
(
Admin) |
Delete