Polymorphism: rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581
rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 ( SNPedia | 23andMe )

Variant Type: Haplotype

Factor:
- Symbol: CDKN1A
- Name: cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- Entrez ID: 1026
- Ensembl ID: ENSG00000124762

Ethnicity: Italian
Age of cases: 100
Shorter lived allele: A-G-G-A-T-A
Longer lived allele: non A-G-G-A-T-A haplotypes
Finding: Positive

Statistics
- Number of cases/controls: 184 vs 184 (initial)
- p-value: 0.02249 [0.02249]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Sequenom's chip-based DNA MASSARRAY

Reference:
20126416: Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population.

Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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