Denigma Buck Institute Health Extension
Polymorphism: rs1042522
rs1042522 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 17p13.1

Factor:
- Symbol: p53
- Name: tumor protein p53
- Entrez ID: 7157
- Ensembl ID: ENSG00000141510

Factors:
  • p53 tumor protein p53 ( 7157 / ENSG00000141510 )


    • Description:

    Both p53 codon 72 alleles are equally compatible with extreme longevity.

    Sardinian population was used in replication study.

    Trivial name is Pro72Arg.

    Ethnicity: Italian
    Age of cases: 100+
    Finding: Negative

    Statistics
    - Number of cases/controls: 394 vs 611 (initial) | 110 vs 92 (replication)
    - Significant: No

    Study Design
    - Study type: Candidate Region/Gene
    - Technology: N/A

    Reference:
    10577935: P53 codon 72 polymorphism and longevity: additional data on centenarians from continental Italy and Sardinia.

    Choice: Clean
    Created: June 30, 2013, midnight
    Updated: Aug. 8, 2014, 1:05 p.m.

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